Jigsaw MagSRT® includes three B Vitamin co-factors because they work synergistically to help the magnesium absorb in your body.
What is Quatrefolic® (Folate, Vitamin B9), and why is it included?
Quatrefolic® (5-MTHF, or folate) is an active form of Vitamin B-9, folic acid. For many people, it is difficult to convert folic acid into folate.
Folate is an important co-factor to P5P and beneficial to many bodily functions. Together, these greatly improve Magnesium’s function to support optimal health.
Why is Vitamin B6 (Pyridoxal-5-Phosphate) included?
P5P (Pyridoxal-5-Phosphate), the active form of Vitamin B6, performs over 30 critical enzymatic reactions in the body, including the manufacture of serotonin and dopamine in the brain. The inactive forms of B6 (pyridoxine hydro-chloride, pyridoxal, or pyridoxamine) have to be converted by the liver to the active form (Pyridoxal-5-Phosphate or P5P) the body needs. Individuals with compromised liver function have difficulty making this conversion and consequently may be at risk of a vitamin B6 deficiency.
P5P works synergistically with Magnesium in many ways. A deficiency in either causes many issues where the body depends on both Mg and P5P. It is critical to get both.
Since Vitamin B6 is already difficult to get and convert into its usable form, we give it to you already in its active P5P form. All the benefits are available immediately after absorption - no trouble converting or waiting.
Why is Vitamin B12 (Methylcobalamin) included?
Methylcobalamin, the active form of Vitamin B12, is included as a supporting B vitamin to contribute to the effectiveness of Magnesium.
Additionally, methylcobalamin is a necessary cofactor for your body's ability to properly methylate. Methylation is a cycle that occurs in your body billions of times every second. It's one of the most important biochemical processes for long-term health and essential for the proper function of almost all of your body's systems.
Using the active form of B12 is particularly important because people with chronic conditions are poor methylators -- making it difficult to convert inactive forms into their useful active form.
Do you have a version without the B-Vitamins?
Yes. A number of customers requested the ability to supplement their B-vitamins separately, so we created Jigsaw Magnesium w/SRT® (B-Free).