5-HTP Supplement

Each bottle of Jigsaw Health's 5-HTP supplement delivers 120 capsules of pure, European-source 5-HTP, with 100mg per capsule.


The body uses 5-HTP (5-hydroxytryptophan) to make serotonin, a neurotransmitter that is crucial to maintaining mood. In fact, many expensive alternatives for mood support work- at least in part - by raising serotonin levels in the brain. Providing the body with naturally occurring 5-HTP can help support healthy serotonin levels and promote emotional well being without side-effects.*

5-HTP w/SRT® - NEW with Sustained Release Technology
5-HTP w/SRT® imageMade in the USA

Finally, a 5-HTP That Provides All Of The Benefits — And None Of The Drawbacks!

  • Propriety sustained release technology makes 5-HTP work longer and better.
  • Often allows you to take less... saving you money!
  • Eliminates the nausea that often occurs with 5-HTP.
  • Only the highest quality 5-HTP from Europe, not China.

Customer Rating image 4.9 out of 5
94% of reviewers would recommend this to a friend.

"...has helped tremendously with mood stabilization (calmness) and reduced anxiety..."

Read More Customer Reviews Order Now...

What Makes Jigsaw Health 5-HTP w/SRT® So Unique?

We've taken only the best form of 5-HTP that exists — sourced from a European manufacturer, Linnea, which has the purest form of 5-HTP available — and combined it with our proprietary, sustained release technology (SRT).


Why Is Sustained Release Technology SO Important?

First, 5-HTP has a very short half-life in the body — only about 90 minutes. That means that it is gone from the body very rapidly after being consumed. This is the reason that most people who take 5-HTP often need to take many doses throughout the day in order to maintain the effect.

The other problem with non-sustained release formulas is that when you dump a lot of 5-HTP into the GI tract all at once, it is rapidly converted to serotonin right there. What you really want though, is for the majority of 5-HTP to be converted to serotonin in the brain. So releasing it over a longer period of time allows the 5-HTP to be gradually absorbed and converted where it is most needed... in the brain.

Not only is this better for seeing a more long-lasting effect, but it can also help avoid stomach upset which some people experience as a side effect when 5-HTP is dumped into the intestinal tract all at once.

For most people, sustained release technology will also provide the ability to take a lower dose of 5-HTP, while still having the same — if not even greater — benefits.


What Can 5-HTP Help Me With?*

  • Promote a balanced stress response.*
  • Support restful sleep.*
  • Maintain mental and emotional well-being.*
  • Support stable mood.*

Want To Feel Emotionally and Mentally Better Every Day?*

How long has it been since you could say you felt your best for several days in a row? For as little as Jigsaw Health’s 5-HTP supplement costs, why not give it a try for thirty days. We guarantee your satisfaction, so there is no risk at all. Give it a try... if it doesn't work for you, just call us and you'll get a full refund - including the shipping cost. That's how confident we are that you will see noticeable improvements within just a few weeks.

Is Jigsaw 5-HTP Supplement A Good Value?

Yep. There are times in life when you really do get what you pay for. Don't be fooled by other companies trying to capitalize on the buzz around 5-HTP by selling unrefined, low quality material (often in lower doses and smaller bottle sizes) for less money.

You might as well save your money and use nothing rather than waste even a few dollars on those ineffective options. Jigsaw Health provides 100mg of PREMIUM QUALITY L-5-Hydroxytryptophan (L-5-HTP) per tablet.


What Is The Importance Of Having A European Source?

The importance is having purity you can trust. Jigsaw's L-5-Hydroxytryptophan comes from Linnea, a Swiss manufacturer of active ingredients specializing in the extraction and purification of plant materials and the synthesis of fine chemicals.

Linnea is absolutely committed to conforming with the highest international standards. Due to this commitment, the Linnea name remains a guarantee of the highest purity, efficacy, and safety.

Linnea's in-house Quality Assurance systems and high standards of operation ensure consistency from batch to batch. And all of Linnea's manufacturing processes are fully validated and backed by comprehensive record-keeping and full batch traceability. Compliance with ICH standards (International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use) is certified by Swissmedic (Swiss Health Authority).

Need A Refresher On Why People Take 5-HTP?

5-HTP is an advanced form of tryptophan, the naturally occurring amino acid that tells your brain to produce serotonin — which is used in the brain to promote overall feelings of well-being. Unlike other expensive options, Jigsaw Health’s 5-HTP supplement naturally helps your body maintain a stable mood and a healthy response to stress. We think you’ll find that so many people are recommending Jigsaw’s 5-HTP because it works and it costs just $0.44 per day!*

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Selection List Price Savings
1 bottle $34.97 $34.97 ----------------
2 bottles $69.94 $59.97 $9.97 (14%)
3 bottles $104.91 $79.97 $24.94 (24%)
4 bottles $139.88 $99.97* $40.57 (29%)

120 tablets per bottle = 2 mo. supply. (100mg of 5-HTP per tablet.)

* FREE shipping on orders over $89! ($6.97 if under $89)

Active Ingredient:

L-5-hydroxytryptophan (L-5-HTP from Griffonia simplicfolia seeds).

Suggested Use:

Take 1-2 tablets daily, with or without food, or use as directed by your healthcare professional.*


A 5-HTP supplement should not be taken in conjunction with SSRI medications unless under the direct supervision of a physician.

Use caution when taking 5-HTP and drinking alcoholic beverages, as alcohol may inhibit the metabolism of 5-HTP.

Jigsaw Health 5-HTP w/SRT® contains:

  • No artificial colors
  • No chemical additives
  • No artificial sleep aids
  • No stimulants
  • No dairy
  • No gluten
  • No yeast
  • No GMO (Genetically Modified Organisms)
  • No Peak X
  • No pesticides
  • No preservatives
  • Vegan Safe



Sherri Z.
from Lutz, FL
Tuesday, April 10, 2012


4 out of 5





Pros: It actually works!

Cons: Having to wait for order to come in.

"In the past I have taken Ambien to help me sleep but would feel tired and weak the next morning. Using the 5-HTP helps me relax to get to sleep and stay asleep the entire night. If I use another brand of HTP I go to sleep but cannot sleep through the night."

What's your level of medical/health knowledge? I'm a professional in the medical/health field (Doctor, nurse, lab scientist, etc.)

How often do you shop at JigsawHealth.com? Once every few months

What is your gender? Female

What decade were you born in? 1950s

Elvis or The Beatles?

Show More Results...

Jigsaw Health 5-HTP w/SRT® contains:

  • No artificial colors
  • No chemical additives
  • No artificial sleep aids
  • No stimulants
  • No dairy
  • No gluten
  • No yeast
  • No soy
  • No Peak X
  • No pesticides
  • No preservatives
  • Vegan Safe

What is Serotonin?

Serotonin is a neurotransmitter that plays an important role in the regulation of anger, aggression, mood, sleep, sexuality, and appetite. It is vital for promoting and maintaining overall feelings of well-being and emotional calmness.*


L-5-Hydroxytryptophan (L-5-HTP) can naturally augment serotonin levels when your body is challenged in producing serotonin on its own. Unlike tryptophan, which competes with other amino acids to get to the brain, L-5-HTP is absorbed directly into the brain. L-5-HTP is only one biochemical step away from converting to serotonin. Healthy levels of serotonin are associated with stable mood and a healthy response to stress.*

To make sure you get the highest quality serotonin available, the all-natural form of L-5-HTP is extracted from the seeds of the Griffonia simplicifolia tree found principally in the West African countries of Ghana, Ivory Coast, and Togo. Various parts of the Griffonia simplicifolia tree were traditionally used not only as chewing sticks, but as African healing remedies to treat wounds, nausea, kidney ailments, and more.

More Information:

5-HTP: Supplement Information Courtesy of Natural and Alternative Therapies Database

Related Information:

What change is this?
What sort of chemistry?
I feel different, peaceful.
My tears are of joy!

The sun is shinin'
Just like my smile.

It's easy to see,
With more serotonin,
I feel brand new!

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Thank you for the follow-up note Patrick. I appreciate the personal touch! My husband and I both started on the Essential Packets - so far so good. In fact I placed a reorder today. Unfortunately there seems to be a back order issue. I'll look at this as a good sign that business at Jigsaw is going well. Good for you! I appreciate the products you offer and the ease of placing orders, whether on line or by phone. Thanks!
- Linda

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15863 N. Greenway-Hayden Loop, Ste 120 Scottsdale, AZ 85260

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.