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WELLNESS PIECE BY PIECE
by Pat Sullivan
Jigsaw Health Founder & CEO


Who is Pat Sullivan?
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Arthritis: Conventional and Prescription Medications
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There are well over 100 medications used to treat the many different forms of arthritis and related diseases. Below are some of the most common medications used to relieve the pain associated with joint inflammation:

Analgesics such as acetaminophen – Brand name Tylenol®. Nutrients depleted: Glutathione, which plays a critical part in the detoxification and anti-oxidation processes of the enzyme system. Follow the product label’s instructions carefully. Taking higher doses than what is recommended on the label may lead to possible liver damage.

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
These are the most widely used and prescribed medications, since they reduce pain as well as inflammation.

Prescription COX-2 Inhibitors
Generally, NSAIDs inhibit two naturally occurring enzymatic reactions: Cyclo-oxygenase-2 (COX-2), which triggers pain and inflammation; and Cyclo-oxygenase-1 (COX-1), which prevents blood platelets from clumping together and forming clots, and also helps maintain the stomach lining. Because COX-2 inhibitors selectively block the COX-2 enzyme and not the COX-1 enzyme, these drugs are uniquely different from traditional NSAIDs and may cause less severe gastrointestinal problems. However, the incidence of cardiovascular disease increases significantly when using these drugs. They include:
  • Celebrex®
  • Bextra® (Withdrawn from the market by the FDA)
Over-the-counter NSAIDs
These are the most commonly used NSAIDs. They inhibit both COX-1 and COX-2 enzymes. Inhibition of the COX-1 enzyme results in damage to the stomach lining and causes ulcers and bleeding. Nutrients depleted: folic acid. These drugs include:
  • Ibuprofen – Brand names Advil®, Motrin®, and Nupren®
  • Naproxen – Brand names Aleve®, Anaprox®, Naprelan®, and Naprosyn®
Aspirin
Aspirin reduces inflammation, suppresses fever, and acts as an anticoagulant. Nutrients depleted: Folic acid, iron, potassium, sodium, and vitamin C. More importantly, studies have shown that use of aspirin, especially over the long term, comes with an increased risk of gastrointestinal bleeding.

WARNING: Before taking any NSAID, consult your pharmacist for specific instructions on their proper use and risks. In April of 2005, the FDA issued warnings and made changes to protect the public against the risks of taking prescription and over-the-counter NSAIDs. In particular, NSAIDs can carry an increased risk of cardiovascular disease and gastrointestinal bleeding.

Corticosteroids
These are synthetic forms of naturally occurring hormones produced by the adrenal glands that provide powerful and immediate short-term relief of inflammation. Some brand names are Cortisone®, Hydrocortone®, and Prednisone®. They can be given as injections into the joints to treat flare-ups, administered through use of inhalers (as in the case of asthma), administered orally (in pill form), or topically (in cream form). Nutrients depleted: Calcium, folic acid, magnesium, potassium, selenium, vitamins C and D, and zinc.

Additional Information about Arthritis
  1. Arthritis Overview
  2. Common symptoms of arthritis
  3. Common causes of arthritis
  4. Help me choose a natural and alternative treatment for arthritis
  5. Dietary and lifestyle recommendations that may help in the treatment of arthritis
  6. Cited Sources and Additional Reading for arthritis




Last Updated: Tuesday, February 13, 2007


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